Access to scientific information and knowledge in the framework of the Internet has steadily grown in recent years, with special advantages for the information generated in developed countries. In other parts of the world a number of factors are influencing the capacity to generate and use scientific information online, i.a. connectivity problems, lack of financial resources, weak institutional support and infrastructure, and poor training in the electronic publishing and dissemination tools. Latin America (including the Caribbean) has been relatively slow in adopting the Internet: our users represent today 3.6% of the world’s total, against 36.9% from North America, 30% from Europe and 27% from Asia and the Pacific. The Internet infrastructure shows even lower figures: only 1.6% of the world’s total corresponds to Latin America, with 2.4% of the domains. As a result, only 3% of webpages offer contents in Spanish and 1% in Portuguese, against 75% in English. Against this background, it should be noted that also in Latin America, universities and higher education institutions, as well as national research councils, are active promoters of the web as an ideal means to put local information and knowledge online. Is this purpose being successfully achieved? In partial answer to this question; the present paper refers to a specific experience that has developed on the basis of regional cooperation among national institutions involved in scientific publishing.