This overview of key Open Access (OA) strategies in Brazil over the last three years describes the guidelines, tools and methodologies needed for Brazil to become an effective actor in the worldwide open access movement. We review general trends and awareness of OA, as well as ongoing developments and policies, opportunities and challenges, both national and international. The institutionalization of Brazilian scientific research is described, along with advances in open access journals and repositories, as well as institutional and governmental policies and the problems that have slowed their progress. Among the major actions targeted recently are plans and actions specific to Portuguese-speaking countries, as well as international collaboration. We conclude with challenges and opportunities ahead.